Protein Info for ABZR87_RS13185 in Ralstonia sp. UNC404CL21Col

Annotation: efflux RND transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 402 signal peptide" amino acids 1 to 45 (45 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 59 to 384 (326 residues), 248.6 bits, see alignment E=4e-78 PF16576: HlyD_D23" amino acids 86 to 298 (213 residues), 85.7 bits, see alignment E=5.9e-28 PF13533: Biotin_lipoyl_2" amino acids 90 to 131 (42 residues), 41.3 bits, see alignment 2.1e-14 PF13437: HlyD_3" amino acids 195 to 295 (101 residues), 67.4 bits, see alignment E=3.4e-22

Best Hits

KEGG orthology group: None (inferred from 98% identity to rpf:Rpic12D_1564)

Predicted SEED Role

"Probable Co/Zn/Cd efflux system membrane fusion protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (402 amino acids)

>ABZR87_RS13185 efflux RND transporter periplasmic adaptor subunit (Ralstonia sp. UNC404CL21Col)
MPALRLPYPHSDFTGFSDTRSRPRRRSLPTAVSVALLTGAALLAGCSKDAPKAPDVRPVR
TMTVTSEQGAGTAEFSGDVRPRIESRLGFRVPGKIVARLMDVGATVKKGQVLARLDPTDL
ALAQQSAQAQLSAAKTDRDLAAADLKRYSELFAKGFISAAEQQRHQANYDAAQARYEQAG
AGYRNQVNQAGYATLEADADGVVTGVDAEVGQVVSAGQPVVRVAQTAEKEVVVGIPEDQV
DTLRKSPEVSVKLWADQSRSIPAKVREIAPAADPVTRTYTVKISVPNPPPELKLGMTAVA
TFVRPGGGGDSGGMGVRVPISALLQDQGKNVVWLYDAASQTVKPVPVTVGAPRDNVLLVT
SGLQPGQTIVTAGVHLLKAGQKVMPMAPADQPSAQSAITPRR