Protein Info for ABZR87_RS12840 in Ralstonia sp. UNC404CL21Col

Annotation: TonB-dependent siderophore receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 711 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF07715: Plug" amino acids 68 to 174 (107 residues), 82.7 bits, see alignment E=2.7e-27 TIGR01783: TonB-dependent siderophore receptor" amino acids 70 to 710 (641 residues), 480.7 bits, see alignment E=4.4e-148 PF00593: TonB_dep_Rec" amino acids 266 to 680 (415 residues), 217.4 bits, see alignment E=7e-68

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 45% identity to spe:Spro_2736)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (711 amino acids)

>ABZR87_RS12840 TonB-dependent siderophore receptor (Ralstonia sp. UNC404CL21Col)
MALAARLTCAVLLGAALPTQAIAQSTTGEVSATLPATTAVGRGETAQSPGKGFVARQSAA
GTKTDTPIIETPQSISVVTQQQLDDQKPRGISEALNYTSGAFTALVGASNRYDYVALRGF
NDSSVDNTLLDGLRLMSDQGSYSSFQVDPYFLQRIDVLKGPGSILYGRASPGGVVALTSK
KPLFQPYHEVEVTVGNRNRLEGAFDISGPIDQNGVMAFRVTGLARGMDTQFEHVREQRFA
IAPSLAINFTPDTHLLLQTYLQHDPEGGYHSGVPAEGSIFPRNGRYISRYFFDGDPTVEK
YRRTERMVGYQFEHAFNDRLTVRQNFRYVFGDTRLRQIYGFGWASADELTRYYSGAKEAT
HAYTVDNQLEGKFTTGAVKHTMLFGLDYQKRHVDGFWESGSADPINAFNPVYGSPGLTGV
TASPVDRWLEQTGLYLQDQIAIDRWRLTLGVREDHAKASNLYGTGTPSEWSGSKFTKRAG
VVYLFDNGIAPYFSYSDGFNPSLRADQRGNLLQPATAKQFEAGVRYQPKGSSTMLSAAVF
NLDQENVATKPVGQIYYVPSGKIRTRGVELEARTQVTDTVSVLANYTFTNMKFIESAEGF
VGNTPYQVPRHMASAWVDWTFMPGYTAGMGLRYVGTSWGDNANSFKVPPYTLVDLMLRID
LARWDPSLKGAKLQLSAKNLFNKNYVASCLSNAYCYWGDARNVMATISYQW