Protein Info for ABZR87_RS12820 in Ralstonia sp. UNC404CL21Col

Annotation: IucA/IucC family siderophore biosynthesis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 628 PF04183: IucA_IucC" amino acids 156 to 406 (251 residues), 259.1 bits, see alignment E=4.2e-81 PF06276: FhuF" amino acids 428 to 586 (159 residues), 125.5 bits, see alignment E=2.8e-40

Best Hits

KEGG orthology group: None (inferred from 67% identity to bge:BC1002_6815)

MetaCyc: 64% identical to alcaligin synthetase (Bordetella bronchiseptica)
6.3.2.-; RXN-11012

Predicted SEED Role

"Siderophore [Alcaligin] biosynthesis complex, long chain @ Siderophore synthetase component, ligase"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (628 amino acids)

>ABZR87_RS12820 IucA/IucC family siderophore biosynthesis protein (Ralstonia sp. UNC404CL21Col)
MNVTLQNQLSQHPAQAAAHLTPEVWAQANRLLLRKAIAEYAHEIILEPEHVKDAANGFAL
YQVFSDDGKVCYQFEARRLALRHWFIRPESIRRLVDGAEQPLDALQFIIECRQRLGIRDD
LLPIYLDEISSTLFGSAYKRMKADAPSSAQLADATDFQTIEVAMMEGHPGFVANNGRLGF
NAVDYQAYAPEAGSDIRVIWLAVHKDHATPSTLSTLDYAQLLAEELGQDTVDEFTRQVAA
KGVDPADYHFMPAHPWQWFNKLSIAFAGYVAQRKIICLDYSADHYIAQQSIRTFFNTSDR
TKRYVKTSLSILNMGFMRGLSPYYMSGTPAINEFIKELVSGDAFLRENGFTILQEVAAIG
FRNFYYEAAIPVDTPYKKMFSALWRENPLQLLQPGERLMTMAALLHVDKDGVALMPELIR
RSGLPALTWVRRYLQAYLTPLLHCFYAHDLSFMPHGENLILVMDKHVPVRAIMKDIAEES
AILEIKAREWLPERVQRLAVEVPDNFKLLGIFIDVFDGVLRHINHVLVENGCCTEDEFWG
AVADCVYDYQDAHPERAAKYAHYDMFVPEFLHSCLNRLQLGNNVQMVNLADPASSLKMAG
NLVNPIAKFRRTAQGRSVAAAEAAEAAA