Protein Info for ABZR87_RS12765 in Ralstonia sp. UNC404CL21Col

Annotation: SurA N-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 646 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF13624: SurA_N_3" amino acids 1 to 166 (166 residues), 146.2 bits, see alignment E=2e-46 PF13623: SurA_N_2" amino acids 2 to 143 (142 residues), 100 bits, see alignment E=2.9e-32 PF13145: Rotamase_2" amino acids 250 to 387 (138 residues), 70.3 bits, see alignment E=6.6e-23 PF13616: Rotamase_3" amino acids 263 to 374 (112 residues), 108.9 bits, see alignment E=5.5e-35 PF00639: Rotamase" amino acids 276 to 372 (97 residues), 101.5 bits, see alignment E=1e-32

Best Hits

KEGG orthology group: K03770, peptidyl-prolyl cis-trans isomerase D [EC: 5.2.1.8] (inferred from 97% identity to rpf:Rpic12D_1532)

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8)" (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (646 amino acids)

>ABZR87_RS12765 SurA N-terminal domain-containing protein (Ralstonia sp. UNC404CL21Col)
MLDFVRTHRRLMFLVLLILVFPSFVFFGVQSYSSFMDSSHDAAKVDGKVISTNEVDARVR
EQTERLRQMLGAQYDPRQFEGPQMRRDVLDGIIQQRVLANEVMRANLTISNDKIRDTILQ
IPAVAALRKPDGSFDQEAYVRLLTAQNMTPEQLEGNLRFELSQQQIPQSIVSSAFVPKSL
VERLIQVRDQQREVQTLLFKPADYAAKVNADERAIQAYYDAHQQEFSVPEQVKAEYVVFS
GEDMMKQIPVTPEQIKEYYDQNAARFKTQEERRAAHILIKLPDNAKPADKDAAKKKAEEV
LAEVRKNPASFAELAKKYSGDPGSAAQGGELGFLGKGATVPPFENALFALKQPGDISDVV
QSDFGFHIIKLEEVKGGGVQPLEAVKPELEREVRTQLANKKYSELADAFSNTVEDQSDSL
KPVADKLKLQIQTADNVTRTPSPAQSGSPIGNDKVLKALFADDVIKNHRNTAAIQVGPTT
LVAARAAEYRPATVKKLADVREQVKAKVIAEQAAALAKKAGEEKLAAVKQSNSADGFNAA
QTLSRQQAQGTPPAALTAILRADATKLPVTIGVDLGAQGYALYRINKVLPPANVDEARRT
ADAQQLAQAAGQTEFNAYYEALKARSKVKINSSAVDTSKPANTAED