Protein Info for ABZR87_RS12425 in Ralstonia sp. UNC404CL21Col

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 353 PF00005: ABC_tran" amino acids 28 to 175 (148 residues), 123.7 bits, see alignment E=1.4e-39 PF08402: TOBE_2" amino acids 283 to 349 (67 residues), 35.7 bits, see alignment E=1.1e-12

Best Hits

Swiss-Prot: 50% identical to CYSA_BORPA: Sulfate/thiosulfate import ATP-binding protein CysA (cysA) from Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)

KEGG orthology group: None (inferred from 98% identity to rpf:Rpic12D_1456)

Predicted SEED Role

"Sulfate and thiosulfate import ATP-binding protein CysA (EC 3.6.3.25)" in subsystem Cysteine Biosynthesis (EC 3.6.3.25)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.25

Use Curated BLAST to search for 3.6.3.25

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (353 amino acids)

>ABZR87_RS12425 ABC transporter ATP-binding protein (Ralstonia sp. UNC404CL21Col)
MSTEPLHLAPVPIRLRGCGKHFGGQRVLESMDLDIAAGETVVLLGPSGCGKTTTLRIVAG
LEAPDAGGTVHFGDEDVTARPIERRRVGMVFQNYALFPNLSVRGNVEYGLRIQRRQNGLS
DTQISARANTLLEMMHLTPYADRGVAQLSGGQRQRVALARALAPEPRVLLLDEPLTALDA
KLRESVRAEMDRLLRGLGITTIYVTHDQEEAMALADRIVVMKAGRIAQIGTPREIYFQPA
NRHVADFIGIMNRLDGTREDGAFVCAGGRVRVPDGDGNAIFFRPEDAVLADPAQAALKGT
VESAVFLGFRTRVRVAGVSSTPLFIDVPGRQHFAPGHAVGFDIPADRLLTLQA