Protein Info for ABZR87_RS12335 in Ralstonia sp. UNC404CL21Col

Annotation: adenosylmethionine--8-amino-7-oxononanoate transaminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 468 TIGR00508: adenosylmethionine-8-amino-7-oxononanoate transaminase" amino acids 28 to 449 (422 residues), 512.8 bits, see alignment E=2.9e-158 PF00202: Aminotran_3" amino acids 41 to 445 (405 residues), 324.9 bits, see alignment E=3.2e-101

Best Hits

KEGG orthology group: K00833, adenosylmethionine-8-amino-7-oxononanoate aminotransferase [EC: 2.6.1.62] (inferred from 98% identity to rpf:Rpic12D_1435)

Predicted SEED Role

"Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)" in subsystem Biotin biosynthesis (EC 2.6.1.62)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.62

Use Curated BLAST to search for 2.6.1.62

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (468 amino acids)

>ABZR87_RS12335 adenosylmethionine--8-amino-7-oxononanoate transaminase (Ralstonia sp. UNC404CL21Col)
MAYPPIPVPADGAPSANTAWQARSRAAVWHPCTQNARLDAMPPLPIARGQGPWLIDFDGK
RYLDGTSSWWVNLFGHANPHINAALKTQLDSLEHVMLAGATHRPAVELAERLIELTGGVL
GHSFFGSDGASAVEIALKMSFHAHRNAGQGARSRFVCLEHGYHGETLGALGVTDVAIFRD
AYDPLILQSHRVPSPDARLAGPGETAADVAERALAALRDCLSTHAGTIAAVIIEPLVQCA
AGMAMHDVSYLRGVRALCDEFGVHWIADEIAVGCGRTGTFFACEQAGVWPDLLCLSKGIS
GGYLPLSIVLSRDAIYDAFNDDAPVRSFLHSHSYTGNPLACRAALATLDLFAEEDVFARN
RVTAARIAQGLAPLSHDARFAHLRQTGMITAFDVHPDVAGARFAERFALTARTHGLLLRP
IGNTVYLLPPYVLSDEETDTLVERTLQTLEDTLAQATGETEGHTYAIA