Protein Info for ABZR87_RS12270 in Ralstonia sp. UNC404CL21Col

Annotation: CreA family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 159 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF05981: CreA" amino acids 27 to 151 (125 residues), 179.9 bits, see alignment E=1.1e-57

Best Hits

Swiss-Prot: 56% identical to CREA_SHIFL: Protein CreA (creA) from Shigella flexneri

KEGG orthology group: K05805, CreA protein (inferred from 96% identity to rpi:Rpic_1356)

Predicted SEED Role

"Conserved uncharacterized protein CreA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (159 amino acids)

>ABZR87_RS12270 CreA family protein (Ralstonia sp. UNC404CL21Col)
MRPFTKFPLLIAALALSTVGCSRAEDIGSVSTNFRITGSDKIVIEAFDDPLVQGVTCYVS
RARTGGIKGTLGVAEDVSEAAVACRQVGEISFAKPLPQQDDMFTQRLSLVFKTLHVVRTV
DRKRNVLVYLTYSDKVISGSPKNSVTAVPIPASQPIPVK