Protein Info for ABZR87_RS11820 in Ralstonia sp. UNC404CL21Col

Annotation: type I methionyl aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00500: methionine aminopeptidase, type I
  • amino acids 4 to 254 (251 residues), 315.7 bits, E=1.1e-98
• PF00557: Peptidase_M24
  • amino acids 13 to 247 (235 residues), 187.8 bits, E=1.1e-59

Best Hits

Swiss-Prot: 58% identical to MAP1_RICPR: Methionine aminopeptidase (map) from Rickettsia prowazekii (strain Madrid E)

KEGG orthology group: K01265, methionyl aminopeptidase [EC: 3.4.11.18] (inferred from 100% identity to rpf:Rpic12D_1341)

MetaCyc: 57% identical to methionine aminopeptidase (Escherichia coli K-12 substr. MG1655)
Methionyl aminopeptidase. [EC: 3.4.11.18]

Predicted SEED Role

"Methionine aminopeptidase (EC 3.4.11.18)" (EC 3.4.11.18)

MetaCyc Pathways

• Arg/N-end rule pathway (eukaryotic) (8/14 steps found)
• Ac/N-end rule pathway (6/21 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.18

Protein Sequence (274 amino acids)

>ABZR87_RS11820 type I methionyl aminopeptidase (Ralstonia sp. UNC404CL21Col)
MAVTIHTAEDIAHMRVACRLASEVLDYITPFVVPGVTTGKLDQLCHAYMRDVQGTVPAPL
NYAPPGYPPFPASICTSVNDVICHGIPGDKVLKNGDIVNLDITVITKEGYYGDTSRTFVV
GEGSILAKRLTQVTFECMWKGIAAVRPGARLGDIGHVIQQHAEAAGYSVVREYCGHGIGK
KFHEDPQILHYGRPGTGMELKAGMIFTIEPMINAGKRDIRTMPDQWTVKTRDRSLSAQWE
HTLLVTETGHEVLTVSALTPPAPEFVHEGAPATA