Protein Info for ABZR87_RS11815 in Ralstonia sp. UNC404CL21Col

Annotation: [protein-PII] uridylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 862 PF03445: DUF294" amino acids 23 to 107 (85 residues), 31 bits, see alignment E=6.5e-11 TIGR01693: protein-P-II uridylyltransferase" amino acids 24 to 858 (835 residues), 805 bits, see alignment E=4.6e-246 PF01909: NTP_transf_2" amino acids 62 to 97 (36 residues), 24.7 bits, see alignment (E = 7.6e-09) PF08335: GlnD_UR_UTase" amino acids 167 to 305 (139 residues), 147 bits, see alignment E=1.1e-46 PF01966: HD" amino acids 444 to 541 (98 residues), 32.9 bits, see alignment E=2.1e-11

Best Hits

Swiss-Prot: 90% identical to GLND_RALSO: Bifunctional uridylyltransferase/uridylyl-removing enzyme (glnD) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K00990, [protein-PII] uridylyltransferase [EC: 2.7.7.59] (inferred from 69% identity to bmu:Bmul_1255)

Predicted SEED Role

"[Protein-PII] uridylyltransferase (EC 2.7.7.59)" in subsystem Ammonia assimilation (EC 2.7.7.59)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.59

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (862 amino acids)

>ABZR87_RS11815 [protein-PII] uridylyltransferase (Ralstonia sp. UNC404CL21Col)
MPSAAAAPAEEVQPRDALKAERAHLFAQFDQHANVQQLVTKLARAVDRALVRLWQEEQMP
ADCALIAVGGYGRGELFPYSDVDILLLLPGTADKTLEARLEAFIGRCWDMGLDIGSSVRT
VDECINEAAQDVTVRTSLLEARLLTGDEGLYRTFETHYQGHLDAADFFQSKLLEMRQRHA
KYQDTPYSLEPNCKESPGGLRDLQVILWMTRAAGFGSSWNELLANGLLTRREAQELASNE
RLLKTVRARLHLLAGRRQDVLVFDLQTQLAESFGYRPTTAKRASEQLMRRYYWVAKAVTQ
LNTVVLQNIEARLFPTELGITRRINDRFVERQGMLEIADADLYQREPTAILETFLLYEQT
RGIKGLAASTMRALYNARTLMDAKWRKDPANRALFLSILQQPQGITHALRLMNQTSVLGR
YLVNFRRIVGQMQHDLFHVYTVDQHILMVVRNIRRFSIVEHTHEFPFCSQLMANFDKPWV
LTVAALFHDIAKGRGGDHSVLGMSDARRFCKEHGIAKEDADLIVWLVEHHLTMSQVAQKQ
DLGDPEVIRHFADLVGTERRLTALYLLTVADIRGTSPKVWNAWKGKLLEDLYRMTLRVLG
GATTDPHAVLESRKEEARALLRLAALDDTAHEALWKQLDVGVFLRHDARDIAWFTRHFYN
RVDTTIPIVRARISPAGVGLQVAVYSPDRPDLFARICGYFERKSLTILDAKIHTTKHGYA
LDTFQVADPSSGLVEPGHYRDIITLVEHELAEQISRETALPEPPRGRISRQSRSFPIKPR
VDLRADERGQYYLLSISATDRTGLLYAIARVLAHRRVSVHTARINTLGERVEDIFLVDGT
RLTQDNKLQLELESELLDALAI