Protein Info for ABZR87_RS11705 in Ralstonia sp. UNC404CL21Col

Annotation: dipeptide ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 629 PF00005: ABC_tran" amino acids 41 to 205 (165 residues), 94.6 bits, see alignment E=2e-30 amino acids 350 to 499 (150 residues), 110.7 bits, see alignment E=2.2e-35 PF13304: AAA_21" amino acids 172 to 240 (69 residues), 29.1 bits, see alignment E=2.5e-10 PF08352: oligo_HPY" amino acids 256 to 287 (32 residues), 33.3 bits, see alignment (E = 1.3e-11) amino acids 552 to 588 (37 residues), 39.4 bits, see alignment 1.6e-13

Best Hits

Swiss-Prot: 72% identical to GSIA_PECAS: Glutathione import ATP-binding protein GsiA (gsiA) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K13892, glutathione transport system ATP-binding protein (inferred from 99% identity to rpf:Rpic12D_1318)

Predicted SEED Role

"Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (629 amino acids)

>ABZR87_RS11705 dipeptide ABC transporter ATP-binding protein (Ralstonia sp. UNC404CL21Col)
MTATKQPSASSVIAMPDQRVVQVQDLSVRFATSERVVDAVRNLSFHVDRGETLAVVGESG
SGKSVTSLALMRLVEHGGGKIIGGQMHLRRRNGEVLDLANASPAAMRGVRGADIAMIFQE
PMTSLNPVFTVGEQIAESIRLHQGKPASEAKAEALRMLELVRIPEARNVLGRYPHQLSGG
MRQRVMIAMALSCKPSLLIADEPTTALDVTIQAEILQLIRALQQELHMAVVFITHDMGVV
AEVADRVLVMYKGDRVEEGPSATVFAQPAHPYTRALLSAVPRLGSMQGTDGPARFPLLRV
DGTAAAVDTTPQPAASHDVQPILRVRDLVTRFDVPTGIFGRVTRRVHAVEQVSFDLYPGE
TLALVGESGCGKSTTGRSLLRLVDSQSGSIEFAGQNIGELKGPALQTLRRNIQFIFQDPF
ASLDPRVPVGYSIMEPLLVHKVASGKEAQQRVEWLLDKVGLQAAHASRYPHEFSGGQRQR
ICIARALALNPKVVIADESVSALDVSIQAQIVNLMLDLQKEFGVAFLFISHDMAVVERIS
HRVAVMYLGQIVEIGPRRAIFENPQHPYTKKLMSAVPIADPARRHLKRELSTHEIPSPIR
AVGDLPVVQPLVQVAPDHFVARHSIGGAY