Protein Info for ABZR87_RS11565 in Ralstonia sp. UNC404CL21Col

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 424 transmembrane" amino acids 39 to 60 (22 residues), see Phobius details amino acids 71 to 90 (20 residues), see Phobius details amino acids 101 to 121 (21 residues), see Phobius details amino acids 140 to 159 (20 residues), see Phobius details PF06580: His_kinase" amino acids 188 to 267 (80 residues), 76.7 bits, see alignment E=1.4e-25 PF02518: HATPase_c" amino acids 286 to 382 (97 residues), 38.7 bits, see alignment E=1.2e-13

Best Hits

KEGG orthology group: None (inferred from 94% identity to rpi:Rpic_1226)

Predicted SEED Role

"Autolysin sensor kinase (EC 2.7.3.-)" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (424 amino acids)

>ABZR87_RS11565 sensor histidine kinase (Ralstonia sp. UNC404CL21Col)
MRETPSFNAGEPSGKIARMFANVSFPSLADCLRLARRWVIRYAVIIVINTLIAAVLAFGI
RPEETFWKDFVFSQAIGLSMFSLIGIPRHVLWGDGPPNKKVFPWIIVGAVLIGVPLGQWI
ARTILCLNSVNPEPWRADSLRMSFIIAMLAALGATYFYWSRGKLAALQRQAALDALEREE
AEKQVVRAQLMALQAQIEPHFLFNSLAHVDVLIARDPAGARRLLQHLIGFLRSSLSHARA
EQCTLVQEFALLRAYLDIQALRFGNRLRFSLALDDAIANIVIPPMLIQPLVENAVVHGIE
PAREGGEIALSARLAAGHDGERLVLEVRDTGVGFGNDGATGSGLGLTHVRERLSRLFDGD
ARLTITETVPHGVTIIVELPLAHETAPAPSEADAPEWRCRFSRSAATANATATAALSARA
SAGT