Protein Info for ABZR87_RS11505 in Ralstonia sp. UNC404CL21Col

Annotation: sulfonate ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details PF13379: NMT1_2" amino acids 47 to 273 (227 residues), 47.6 bits, see alignment E=5e-16 TIGR01728: ABC transporter, substrate-binding protein, aliphatic sulfonates family" amino acids 51 to 330 (280 residues), 243 bits, see alignment E=1.9e-76 PF04069: OpuAC" amino acids 72 to 266 (195 residues), 21.6 bits, see alignment E=3.7e-08 PF09084: NMT1" amino acids 90 to 264 (175 residues), 46.2 bits, see alignment E=1.4e-15 PF12974: Phosphonate-bd" amino acids 90 to 264 (175 residues), 38.7 bits, see alignment E=1.9e-13

Best Hits

Swiss-Prot: 52% identical to SSUA_ECOLI: Putative aliphatic sulfonates-binding protein (ssuA) from Escherichia coli (strain K12)

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 98% identity to rpf:Rpic12D_1277)

MetaCyc: 52% identical to aliphatic sulfonate ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-56-RXN [EC: 7.6.2.14]

Predicted SEED Role

"Alkanesulfonates-binding protein" in subsystem Alkanesulfonate assimilation or Alkanesulfonates Utilization or Putative sulfate assimilation cluster

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (343 amino acids)

>ABZR87_RS11505 sulfonate ABC transporter substrate-binding protein (Ralstonia sp. UNC404CL21Col)
MTIDIQRRRLLSATVAGASLATLGPVAHAANAATAAPAAAGLPKVTPPAQLRIGFQKSAV
NLVIVKENRALEQRFPGTKISWLEFPAGPQQLEALSAGSLDLAITGDTPPVFAQAAGKDL
RYVGVEPPKPDSSAILVQQDSTLKTLADLKGKRVALQKGSSAHFLIVRGLQKGGLSFADI
QPVYLTPADARAAFERGSVDAWGIWDPYYAATELAIKPRVLATGRTLSSNNSFYFAPTAF
TEKHGDTIAAIFAELSRADRLVQENRKEAAQRIAEFSGLSLATVHLFLSRRPPSPVRPVT
PEAVAEQQRVADAFHGLGLIPRPVKPVELVWHPTPAQLAIARA