Protein Info for ABZR87_RS11335 in Ralstonia sp. UNC404CL21Col

Annotation: ferredoxin--NADP reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 PF00970: FAD_binding_6" amino acids 16 to 98 (83 residues), 37.8 bits, see alignment E=2.1e-13 PF00175: NAD_binding_1" amino acids 113 to 230 (118 residues), 29.5 bits, see alignment E=1e-10

Best Hits

Swiss-Prot: 77% identical to FENR_AZOVI: Ferredoxin--NADP reductase (fpr) from Azotobacter vinelandii

KEGG orthology group: K00528, ferredoxin--NADP+ reductase [EC: 1.18.1.2] (inferred from 99% identity to rpi:Rpic_1180)

Predicted SEED Role

"Ferredoxin--NADP(+) reductase (EC 1.18.1.2)" in subsystem Biogenesis of cytochrome c oxidases (EC 1.18.1.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.18.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (258 amino acids)

>ABZR87_RS11335 ferredoxin--NADP reductase (Ralstonia sp. UNC404CL21Col)
MSAFNQETVLSVHHWNDSLFSFKTTRDQALRFHNGHFVMIGLEVEGKPLMRAYSIASPNY
EEHLEFFSIKVQNGPLTSRLQHLKVGDKLLVSKKPVGTLVLDDLLPGKNLYLFGTGTGLA
PFMSIIQDPDTYERFEKVVLLHGVRQVSELAYADFITSELPNNEFFGDQVREKLIYYPTV
TREPFRNMGRLTDLVDSGKLSADIGLPPMDPAVDRAMICGSPAMLEDTCKLLDARGFKIS
PRMGEAGDYVIERAFVEK