Protein Info for ABZR87_RS10795 in Ralstonia sp. UNC404CL21Col

Annotation: DNA polymerase III subunit gamma/tau

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 734 TIGR02397: DNA polymerase III, subunit gamma and tau" amino acids 3 to 360 (358 residues), 419.6 bits, see alignment E=5.7e-130 PF13177: DNA_pol3_delta2" amino acids 20 to 183 (164 residues), 133.4 bits, see alignment E=1.6e-42 PF00004: AAA" amino acids 42 to 176 (135 residues), 40.8 bits, see alignment E=5.9e-14 PF12169: DNA_pol3_gamma3" amino acids 237 to 365 (129 residues), 71.9 bits, see alignment E=1e-23

Best Hits

KEGG orthology group: K02343, DNA polymerase III subunit gamma/tau [EC: 2.7.7.7] (inferred from 92% identity to rpi:Rpic_1035)

Predicted SEED Role

"DNA polymerase III subunits gamma and tau (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (734 amino acids)

>ABZR87_RS10795 DNA polymerase III subunit gamma/tau (Ralstonia sp. UNC404CL21Col)
MSYQVLARKWRPRDFTTLVGQEHVVKALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAK
SLNCVGADGQGGITAQPCGVCRACTEIDAGRFVDYIEMDAASNRGVDEMAQLLDRAVYAP
TSGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSRCLQFNL
KQMPPGHIVSHLDRILGEEGIAHEPNALRLLAAAAQGSMRDALSLTDQAIAYSAGEVSEA
AVRGMLGAIDQSYLVRLLDALADENGAALVEIADEMAGRSLSFSGALQDLASLLQKIALA
QVVPAAVQDDWPEADDVRRLAERFDAQSVQLFYQFANLGRNELALAPDEYAGFTMTLLRM
LAFQPGQSGGDAAPPSGGGGGKRAMPLAATPATSTRPAVTATAPITAPVTQAAPVATRAE
PMVEAPRATYQATPTAPAPVPVAAAVQAPAAAPARRSPAMEALAAARQASSRGRGGASAP
AATPVAAPAPVARPAPVAGPRPNPAVPASTSSPQRREPPVAAAAPSDDGPPPWDEMPGEL
ASPSLEEMDAAFAGWDSASSVRPGAPEPAARPAQIEAPVAASAPAPTKAVPPEPVAAATP
PDLSASGLTTFDGNWPALAASLPIRGLAQQLAYQSELAAVEGATMRLRVPLPPLTDANVV
ERLEAALTEHFGTPVRVACDIGPARATAAAVDAEQRAERQRNAEEAIAANPFVQALVRDF
AAQVVPGSIQPHAH