Protein Info for ABZR87_RS10555 in Ralstonia sp. UNC404CL21Col

Annotation: MBL fold metallo-hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 261 PF00753: Lactamase_B" amino acids 14 to 103 (90 residues), 48.7 bits, see alignment E=9e-17 PF12706: Lactamase_B_2" amino acids 28 to 212 (185 residues), 63.4 bits, see alignment E=2.3e-21

Best Hits

KEGG orthology group: None (inferred from 96% identity to rpf:Rpic12D_1085)

Predicted SEED Role

"Metal-dependent hydrolases of the beta-lactamase superfamily I" in subsystem Beta-lactamase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (261 amino acids)

>ABZR87_RS10555 MBL fold metallo-hydrolase (Ralstonia sp. UNC404CL21Col)
MTLRFASLGSGSEGNALLVESASGATCTRILLDCGFGIRETVRRLERLGCTPESLNAILV
THEHSDHVGSAYAVAAKFNIPVWTSHGTYRATENLRGADRAAVRFCRADDVFSVGDLQIL
PYTVPHDAREPLQFVFNDGARRLGVLTDAGMSTEYLCTHLAGMHALVLECNHDRDMLANS
AYPWSLKRRIGGDFGHLANDIAAAILTRVRHDALHTVVAAHLSKQNNTPLLAAEAIAAPL
GACVEDVPIADQEEGLLWRTV