Protein Info for ABZR87_RS10135 in Ralstonia sp. UNC404CL21Col
Annotation: beta-ketoacyl-ACP synthase III
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 99% identical to FABH_RALPJ: 3-oxoacyl-[acyl-carrier-protein] synthase 3 (fabH) from Ralstonia pickettii (strain 12J)
KEGG orthology group: K00648, 3-oxoacyl-[acyl-carrier-protein] synthase III [EC: 2.3.1.180] (inferred from 99% identity to rpf:Rpic12D_0980)MetaCyc: 39% identical to 3-oxoacyl-(acyl-carrier-protein) synthase III (Agrobacterium fabrum C58)
RXN-22027
Predicted SEED Role
"3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180)" (EC 2.3.1.180)
MetaCyc Pathways
- superpathway of fatty acids biosynthesis (E. coli) (50/53 steps found)
- superpathway of fatty acid biosynthesis II (plant) (38/43 steps found)
- superpathway of fatty acid biosynthesis I (E. coli) (14/16 steps found)
- 8-amino-7-oxononanoate biosynthesis IV (5/5 steps found)
- fatty acid biosynthesis initiation (type II) (3/3 steps found)
- superpathway of fatty acid biosynthesis initiation (4/5 steps found)
- streptorubin B biosynthesis (20/34 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.3.1.180
Use Curated BLAST to search for 2.3.1.180
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (326 amino acids)
>ABZR87_RS10135 beta-ketoacyl-ACP synthase III (Ralstonia sp. UNC404CL21Col) MTRFARIIGTGSYLPPKRVTNDELAAQLAEKGIETSDDWIVSRSGIRARHFAEPDVTCSD LAVKAAERAIEAAGIDRSELDLILVATSTPDFVFPSTACLVQQKLGITNGCAAFDVQAVC SGFVYALATADKFIRSGAYRNVLVIGSEVFSRIIDFSDRTTCVLFGDGAGAVVLQASDEP GILSTALHADGSHANILCVPGNVAAGAIQGSAFLYMDGQAVFKLAVTVLDKVAREALAAA ELDASQVDWLIPHQANIRIMQGTTKKLGLSNERLIVTVDEHGNTSAASIPLALDVAVRDG RIQRGQHVMLEGVGGGFTWGAALLRF