Protein Info for ABZR87_RS09640 in Ralstonia sp. UNC404CL21Col

Annotation: M48 family metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 419 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 68 to 87 (20 residues), see Phobius details amino acids 99 to 127 (29 residues), see Phobius details amino acids 148 to 168 (21 residues), see Phobius details amino acids 175 to 195 (21 residues), see Phobius details amino acids 291 to 310 (20 residues), see Phobius details amino acids 330 to 350 (21 residues), see Phobius details PF16491: Peptidase_M48_N" amino acids 26 to 204 (179 residues), 201.5 bits, see alignment E=1.1e-63 PF01435: Peptidase_M48" amino acids 207 to 414 (208 residues), 120.7 bits, see alignment E=6.8e-39

Best Hits

KEGG orthology group: K06013, STE24 endopeptidase [EC: 3.4.24.84] (inferred from 99% identity to rpi:Rpic_0812)

Predicted SEED Role

"macromolecule metabolism; macromolecule degradation; degradation of proteins, peptides, glycopeptides"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.24.84

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (419 amino acids)

>ABZR87_RS09640 M48 family metallopeptidase (Ralstonia sp. UNC404CL21Col)
MPAFTAVFLIALVLMSATRLWLAARQVRHVARHRDAVPAQFAESITLDMHRKAADYTIAR
TRLAMLEVPVQAALLIALTLLGGLNWINQAWLGVFGPGYAYGVALIASVIAISSVIELPF
SLYAQFVVEERFGFNRMTFKLWLADNLKGLAIGTVLGLPLLLAVLWLMDKMGAHWWLYTW
VVWMAFMLFVQAIYPNVIAPLYNKFTPLQDEEMRSRIESLLKRCGFASKGLFVMDGSRRS
AHGNAYFSGFGATKRIVFFDTLLARLNPSEMEAVLAHELGHFKRHHITKRIAVTFVLSLG
ALALLGWLMTRTWFYLGLGVAPNLFSDNHALALMLFFLVLPVFTFFISPLASLSSRKDEY
EADAFAAEHADANQLVSALVKLFQDNASTLTPDPVYSTFYYSHPTASQRVERLVQARAA