Protein Info for ABZR87_RS08515 in Ralstonia sp. UNC404CL21Col

Annotation: type II and III secretion system protein family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 630 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details PF13629: T2SS-T3SS_pil_N" amino acids 96 to 164 (69 residues), 67.3 bits, see alignment E=8e-23 PF00263: Secretin" amino acids 330 to 499 (170 residues), 140.7 bits, see alignment E=3.6e-45

Best Hits

KEGG orthology group: K02280, pilus assembly protein CpaC (inferred from 78% identity to rsc:RCFBP_20759)

Predicted SEED Role

"Type II/IV secretion system secretin RcpA/CpaC, associated with Flp pilus assembly" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (630 amino acids)

>ABZR87_RS08515 type II and III secretion system protein family protein (Ralstonia sp. UNC404CL21Col)
MNRLITQRGETRCMGTYMKATAAAVAMLGGLWAGAAHAQVGVESAILTNNAAAPAKPMRM
SASGPIQLTIGSASNAEASRDSAPKGPNCTGAMREHSEVTVPIGKSTMVQLPEAVRSRTV
GNPRVVQAMLVSPQTLYVLGLEVGSTNMIVQGRSGSCTVIDVSVGADPAGLQAALRRLVP
GAKNVEVSAAADSIVLGGTVSDSVQAQKIVDIANAFVTRQSRGPVREEGGGGQQATGQMN
AGGQNGAPLRSPRIINMMAVEAPQQVMLEVKVAEVSKTLIDQMGSALNVAGAFGSWSVGA
LANFLSGSNDIVNFSKNNRLPLKFALDAQKGDGLVKVLAEPSLMAISGQEASFLAGGKIF
IPVAQGGSVGGVSTIVLQEETFGVGLRFTPTVMENGRINLKVSPEVSELSPTGVSVTSPS
TNNTQILPLITTRRASTTLQVHDGQSFAIGGLIKNNITGSLKAIPGVGELPVIGALARST
SFQQDQTELVFVVTPRLVKPLPADYPLPTDTFGQVNTGEILLNGNMEGHKAKPVKAPAAM
AAPASALPAPKATEAAPAAAAAPAAQPVQAPAPTANAPAAADTAAEAQAPAAATVPAAPA
DNGTPPAPAPMAPAPNARRFVSMGEQPFHD