Protein Info for ABZR87_RS08120 in Ralstonia sp. UNC404CL21Col

Annotation: Ku protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 304 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR02772: Ku protein" amino acids 3 to 265 (263 residues), 334.5 bits, see alignment E=2.2e-104 PF02735: Ku" amino acids 11 to 195 (185 residues), 174 bits, see alignment E=1.7e-55

Best Hits

Swiss-Prot: 52% identical to KU_PSEAE: Non-homologous end joining protein Ku (ku) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K10979, DNA end-binding protein Ku (inferred from 96% identity to rpf:Rpic12D_0489)

Predicted SEED Role

"Ku domain protein" in subsystem DNA Repair Base Excision

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (304 amino acids)

>ABZR87_RS08120 Ku protein (Ralstonia sp. UNC404CL21Col)
MPRVIWKGAVSFGLVHIPVALYPATRSDDLDFDWLDRRTMDRVGYKRINKTTGKEVPREQ
IVRGYAYEKDRYVILTDEDIRAANPVSTQTVDLLTFVDAAEIPFLYLDTPYFLAPDRRGE
KVYALLREALTRSQKIGVANVVLHTKQHLAALIPMGPVLVLHTLRWSNEVRDWSELDLPE
EGAKATKLTAKEIDMAEKLIDDMSGKWDPAEYHDTFRDDILTLVDRKVREGRTESVEPME
AETAAPRSGNVIDLTDLLRQSLAKRGKGKAASNDEAEDEPAPRKRAPRKAAAKTARKTAT
RKRA