Protein Info for ABZR87_RS07760 in Ralstonia sp. UNC404CL21Col

Annotation: HlyC/CorC family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 297 PF00571: CBS" amino acids 131 to 185 (55 residues), 29.3 bits, see alignment E=9e-11 PF03471: CorC_HlyC" amino acids 205 to 278 (74 residues), 67.1 bits, see alignment E=1.1e-22

Best Hits

Swiss-Prot: 46% identical to CORC_BUCAI: Magnesium and cobalt efflux protein CorC (corC) from Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)

KEGG orthology group: K06189, magnesium and cobalt transporter (inferred from 99% identity to rpi:Rpic_0404)

Predicted SEED Role

"Magnesium and cobalt efflux protein CorC" in subsystem Copper homeostasis: copper tolerance or Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (297 amino acids)

>ABZR87_RS07760 HlyC/CorC family transporter (Ralstonia sp. UNC404CL21Col)
MNDPYPSPKPADKPRSLLERLTDLISPEPESRAELLEILQDAHARSLIDADSLSMIEGVF
QVSDLCARDIMIPRAQMDALNIADAPSEFIPFVQEAAHSRFPVYEGSRDNIIGILLAKDL
LRFYTDEGFDVRDMLRPAVFIPESKRLNVLLRDFRVNRNHIAIVVDEYGGVAGLITIEDV
LEQIVGDIEDEYDFDQEEDNILPTADGHMRVRGLTEISQFNEAFGTHFSDEDVDTVGGLL
SNHLGRVPHRGEKIVMGTLQFDVLRADARQVQVLLVRRLTAPAGGNATADTSGSHPA