Protein Info for ABZR87_RS07205 in Ralstonia sp. UNC404CL21Col

Annotation: UvrD-helicase domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 670 PF00580: UvrD-helicase" amino acids 50 to 280 (231 residues), 80.4 bits, see alignment E=1.9e-26 PF13245: AAA_19" amino acids 51 to 278 (228 residues), 35.8 bits, see alignment E=8.7e-13

Best Hits

Predicted SEED Role

"ATP-dependent DNA helicase UvrD/PcrA" in subsystem DNA repair, bacterial UvrD and related helicases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (670 amino acids)

>ABZR87_RS07205 UvrD-helicase domain-containing protein (Ralstonia sp. UNC404CL21Col)
MIDPLANFIQEDDARWASQLMGLGPDAFSSVEGDDSRLRAMLSLETADFEACPGSGKTTL
LVAKLAVLAKRWPYRQRGICVLSHTNAARNEIGERLSNSAAGISLLRYPHFVGTIHSFVN
EYLAIPWLRSKGNPVQMIDTQVALSRRMKSLEWKWRFVLEKRQLSEYALMYAATDYTGGD
KGKLGRDSDLYKRLVEAARSSSEQGYFCFDEMFVWANELLDKRPEVAYDLRARFPLLFID
EAQDNSEEQSALLHRIFCAGDSPSRRQRFGDSNQAIYAHSGQEGAATDRFPSGSKHDIPR
SYRFCQAMADEVKGFGVAPQMLIGAGPTSTKIAAGPKAPVLFLFDDESVREVLPRYGAHL
VSCFGERDLANGTYVAVAGVHELDKEDPIPRAMGHYQPSYDPACAKKESAPGSLIQYLAR
ARVGIVKAGNTHVAVDALASALLAVSDLLGKPHPGFNHRSAHRRLLDVLLDASAREAYLK
LVDMVITEQAAFDAAAWNAKVLPLVHAVVGGLSNDAVLTDDAKAFLEWSPATIKEEREDV
PGSPTSNHFGYPRDVPKVEIRLGSIHSVKGETHTATLVLDSFYHKHHLSELKPWLLGTRV
GGSSAGKNGKVVMEGVRMLGRLKLHYVAMTRPSHLLCLAMRKDAFVEEELGILTARGWQI
VDCSAPAENG