Protein Info for ABZR87_RS07055 in Ralstonia sp. UNC404CL21Col

Annotation: ribosome-associated translation inhibitor RaiA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 117 TIGR00741: ribosomal subunit interface protein" amino acids 1 to 103 (103 residues), 98.5 bits, see alignment E=1.3e-32 PF02482: Ribosomal_S30AE" amino acids 4 to 97 (94 residues), 93.7 bits, see alignment E=4.9e-31

Best Hits

Swiss-Prot: 84% identical to HPF_CUPNH: Ribosome hibernation promoting factor (hpf) from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)

KEGG orthology group: K05808, putative sigma-54 modulation protein (inferred from 100% identity to rpf:Rpic12D_0289)

Predicted SEED Role

"Ribosome hibernation protein YhbH" in subsystem Ribosome activity modulation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (117 amino acids)

>ABZR87_RS07055 ribosome-associated translation inhibitor RaiA (Ralstonia sp. UNC404CL21Col)
MNFKLSGHHLDITPALREYVETKLERVIRHFDQVIGVSVLLSVDNHKEKDRRQYAEINLH
LKGKDVFVESHHEDLYAAIDLLVDKLDRQVIKYKDRVQGHDRDSMKHQAFQAVQMQQ