Protein Info for ABZR87_RS07005 in Ralstonia sp. UNC404CL21Col

Annotation: lipoprotein insertase outer membrane protein LolB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 207 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details TIGR00548: outer membrane lipoprotein LolB" amino acids 3 to 175 (173 residues), 69.2 bits, see alignment E=1.8e-23 PF03550: LolB" amino acids 46 to 207 (162 residues), 125 bits, see alignment E=1.4e-40

Best Hits

Swiss-Prot: 92% identical to LOLB_RALPJ: Outer-membrane lipoprotein LolB (lolB) from Ralstonia pickettii (strain 12J)

KEGG orthology group: K02494, outer membrane lipoprotein LolB (inferred from 92% identity to rpi:Rpic_0252)

Predicted SEED Role

"Outer membrane lipoprotein LolB precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (207 amino acids)

>ABZR87_RS07005 lipoprotein insertase outer membrane protein LolB (Ralstonia sp. UNC404CL21Col)
MAMRFTRALGALMLGAGCVLFSGCASLRPANDLFAGTQDADATITRYQGRFSARYTQNNT
EQSAVGSFLWRERGADVQLELMSPLGQTLAIVSQSNQGATLELPNQPPRRAPEVDTLMQD
ALGFSLPVSGLRDWLRARPAPGTPARVARDAQSRPETIEQNGWTVRYVAWADNGNNADGA
KASIRRLDLDRQHGANGPLSVRLVLDQ