Protein Info for ABZR87_RS06980 in Ralstonia sp. UNC404CL21Col

Annotation: aminoacyl-tRNA hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 TIGR00447: aminoacyl-tRNA hydrolase" amino acids 2 to 197 (196 residues), 204.8 bits, see alignment E=4.9e-65 PF01195: Pept_tRNA_hydro" amino acids 4 to 197 (194 residues), 220.3 bits, see alignment E=9.6e-70

Best Hits

Swiss-Prot: 98% identical to PTH_RALPJ: Peptidyl-tRNA hydrolase (pth) from Ralstonia pickettii (strain 12J)

KEGG orthology group: K01056, peptidyl-tRNA hydrolase, PTH1 family [EC: 3.1.1.29] (inferred from 98% identity to rpi:Rpic_0248)

Predicted SEED Role

"Peptidyl-tRNA hydrolase (EC 3.1.1.29)" (EC 3.1.1.29)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.1.29

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (200 amino acids)

>ABZR87_RS06980 aminoacyl-tRNA hydrolase (Ralstonia sp. UNC404CL21Col)
MIKLIVGLGNPGAEYAATRHNAGFWLVDQLARMGNVTLRNETRFHGYAARANLWGNEVWL
LEPQTFMNRSGLATVALARFYKVMPDEILVVHDELDLPPGTVKLKLGGGSGGHNGLKDIA
AHLTTQQFWRLRLGIGHPRNLLPPGSPASGQHDVANFVLKAPRKEEQDLIDRAIDQSLDA
LPELIAGNAEKAMMRLHTAR