Protein Info for ABZR87_RS06960 in Ralstonia sp. UNC404CL21Col

Annotation: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD" amino acids 21 to 173 (153 residues), 120.4 bits, see alignment E=3.8e-39 PF03602: Cons_hypoth95" amino acids 26 to 173 (148 residues), 138.7 bits, see alignment E=5.4e-44 PF05175: MTS" amino acids 68 to 169 (102 residues), 28.1 bits, see alignment E=4.5e-10 PF13847: Methyltransf_31" amino acids 70 to 176 (107 residues), 32.1 bits, see alignment E=2.6e-11 PF13649: Methyltransf_25" amino acids 72 to 165 (94 residues), 30.8 bits, see alignment E=1.2e-10 PF13578: Methyltransf_24" amino acids 84 to 168 (85 residues), 28.4 bits, see alignment E=7.8e-10

Best Hits

KEGG orthology group: None (inferred from 94% identity to rpf:Rpic12D_0271)

Predicted SEED Role

"Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-)" (EC 2.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.-

Use Curated BLAST to search for 2.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (218 amino acids)

>ABZR87_RS06960 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD (Ralstonia sp. UNC404CL21Col)
MAPRTSSSKGPKAKTATSHARAPQQVRIIGGQYKRTPLPVVDADGLRPTSDRVRETVFNW
LGQDLTGWRCADIFAGTGALGFEAASRGAAHVTLIENHAPAVRALHAIRDKLGARMVDIV
SGDAFAWLARQPDAALDAVFIDPPFAQDWTLRALEAATRVVKPGGVIYVEAAQPLVDVSA
DSHDAEPAAGLALPADLVLHKHLRAGAVHAHLLLRKNG