Protein Info for ABZR87_RS06185 in Ralstonia sp. UNC404CL21Col

Annotation: TonB-dependent siderophore receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 759 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF07715: Plug" amino acids 70 to 169 (100 residues), 73.8 bits, see alignment E=1.5e-24 TIGR01783: TonB-dependent siderophore receptor" amino acids 72 to 756 (685 residues), 269 bits, see alignment E=5e-84 PF00593: TonB_dep_Rec_b-barrel" amino acids 258 to 728 (471 residues), 173.2 bits, see alignment E=1.8e-54

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 98% identity to rpf:Rpic12D_0108)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (759 amino acids)

>ABZR87_RS06185 TonB-dependent siderophore receptor (Ralstonia sp. UNC404CL21Col)
MSAAQIERKRTEHSVVGYLTGAMSFAVASAPALADTKKDAVSATLPEQTVTGTNGFKADA
ASGGKFTAPLLDTPKSVTVIPAEVLQGTGSVTLTEALRTVPGIAFGAGEGGNPVGDRPFI
RGYDAQASTFLDGLRDIGAQSREMFNVESVEVIKGPSGAYEGRGAAGGAVNIVTKTPKLE
HFTEGTLSVGNAAYKRVTADGNYQIGEHAAFRLNAMAHDAAVAGRDVTSFSRWGIAPSIA
FGLGTPTRATLSYYHLQSNDTPDTGIPYNNGTFNRRTDGRLQLFAAGDGAPVNVDRNVYY
GLSRDFRRDRADMGTFTLEHDVSSALKLRNTTRVARTSQDTLWTQPDDSQGNIYYGMVWR
RTNSRYSVANTVANQTEATGKFDTGGLKHSYAAGLEFSRERSRNDTYNVATGSNRCPNGI
GAAGGYNCADLFNPNPNDPWAGSIKLSNNPAETTVRTQSAYVFDTIELSPRWQVNGGLRF
DRYSASATTSANAQGVRSSFSRDDNLLNYQLGLVFKPAQNGSIYLAYGTSSTPSGSVAGQ
GADTSALTPDRSGNRGDVLAPEKNRAYELGTKWHVLDSKLALTAAIFRIETTNARIVQQD
GTAAMAGNKRVDGFELGWSGALTNRWQVFGGYTYLKSELRNNGGAGAAFGGTNGTAFPNT
PKNSFSLWTTYQPMPKLTLGGGAYYVSKVWGSANPANPKWVPAYWRFDAMAAYRIDKHTT
LQLNVQNVFDKVYFNQAYASHYASLAPGRTAILTLGIRY