Protein Info for ABZR87_RS05895 in Ralstonia sp. UNC404CL21Col

Annotation: amino acid ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 PF00005: ABC_tran" amino acids 17 to 165 (149 residues), 129.5 bits, see alignment E=1.4e-41

Best Hits

Swiss-Prot: 57% identical to GLNQ_BACSU: Glutamine transport ATP-binding protein GlnQ (glnQ) from Bacillus subtilis (strain 168)

KEGG orthology group: K02028, polar amino acid transport system ATP-binding protein [EC: 3.6.3.21] (inferred from 85% identity to bgl:bglu_2g09490)

MetaCyc: 59% identical to cystine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Amino acid ABC transporter, ATP-binding protein yhdZ"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.21

Use Curated BLAST to search for 3.6.3.21 or 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (258 amino acids)

>ABZR87_RS05895 amino acid ABC transporter ATP-binding protein (Ralstonia sp. UNC404CL21Col)
MIEIKDLHKSFGGVRVLNGISLNVQQGEVVCLIGASGSGKSTLLRCINALESYDSGEIKL
LDQLVEQRCRNINQLRTQVGMVFQRFNLFPHRTALENVMEGPVHVKREPPDQARTEAIAL
LHKVGLGEKTHAYPHQLSGGQQQRVAIARSLAMKPKAILFDEPTSALDPELVGEVLSVMR
TLAREGMTMLVVTHEMGFAREVADRVCFLHAGRIIEEGCAKEVLSAPREARTREFLRHVL
THRVDGSDPLTGGAGAVA