Protein Info for ABZR87_RS05740 in Ralstonia sp. UNC404CL21Col

Annotation: AAA family ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 406 PF07728: AAA_5" amino acids 174 to 308 (135 residues), 26 bits, see alignment E=8e-10 PF00004: AAA" amino acids 175 to 311 (137 residues), 54.9 bits, see alignment E=1.3e-18

Best Hits

KEGG orthology group: None (inferred from 69% identity to rpi:Rpic_2926)

Predicted SEED Role

"ATP-dependent protease La (EC 3.4.21.53)" in subsystem Proteolysis in bacteria, ATP-dependent (EC 3.4.21.53)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.53

Use Curated BLAST to search for 3.4.21.53

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (406 amino acids)

>ABZR87_RS05740 AAA family ATPase (Ralstonia sp. UNC404CL21Col)
MNVPRKSPEYPPGFVPLRELAVLRSPASWALLVPSTTYTVLDAAEQAKVDLAEVKEDEPE
SRSPQPPTVAATEVVPARRRTRGRHIHVFAQEALEQASANLQTADRYQQKHAKALLEQAA
TNDGYRELPRIQPALKKLKEAHSSLGNLREPIQKLTIDLTLAAAMRAKDFRVRPILLTGE
PGVGKTQFALQLAEILGVPMQKWSAGSAQANFQLTGGDSAWRSARPGMIFDMLAKGSSAT
PVLVLDEVDKIGDDGRYPVTPVLLDLLDTETACASQDAFLRMPFDASRIICVLTANDVDA
VPPALLSRVEVFDIRAPDPEQRLQIILAEAQRLQRATGRRIELDIHAADALAERSDLDLR
KTHRLVQDAFATAMASGKLIAVPMMPKRVGAQSIGFVAGSRSNAGN