Protein Info for ABZR87_RS05660 in Ralstonia sp. UNC404CL21Col
Annotation: ornithine--oxo-acid transaminase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 53% identical to OAT_BORPA: Ornithine aminotransferase (rocD) from Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
KEGG orthology group: K00819, ornithine--oxo-acid transaminase [EC: 2.6.1.13] (inferred from 98% identity to rpi:Rpic_0052)MetaCyc: 45% identical to ornithine-delta-aminotransferase (Arabidopsis thaliana col)
Ornithine aminotransferase. [EC: 2.6.1.13]
Predicted SEED Role
"Ornithine aminotransferase (EC 2.6.1.13)" in subsystem Arginine and Ornithine Degradation or Dimethylarginine metabolism (EC 2.6.1.13)
MetaCyc Pathways
- L-citrulline biosynthesis (7/8 steps found)
- L-arginine degradation VI (arginase 2 pathway) (4/4 steps found)
- L-arginine degradation I (arginase pathway) (3/3 steps found)
- L-ornithine biosynthesis II (3/3 steps found)
- L-proline biosynthesis III (from L-ornithine) (3/3 steps found)
- L-arginine degradation XIII (reductive Stickland reaction) (4/5 steps found)
- superpathway of L-citrulline metabolism (9/12 steps found)
- L-Nδ-acetylornithine biosynthesis (5/7 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.6.1.13
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (408 amino acids)
>ABZR87_RS05660 ornithine--oxo-acid transaminase (Ralstonia sp. UNC404CL21Col) MTTAMQHPSYALEDRYGARNYAPLPVMLERGEGVWLFDTDGRRYLDMMSAYSAVSFGHSH PKLVAALIEQAGRLTLTSRAFHNVELGPFLADVCRITRMDRALPMNTGAEAVETAIKAAR KWARDVKGLAPEAAEIIVFENNFHGRTTTIVGFSSHDQYRYGFGPFAAGFRRIPFGDADA LRAAIGPNTGAILMEPVQGEGGIVEPPPGYLKLARELATRHNVLLICDEVQTGLGRTGDV LASWHEGVDADLVVLGKALGGGMVPVSAIAGREAVIGVFRPGDHGSTFGGNPLAAHIGRA ALALLMEEQLPQRAARVGAAFINELKTLVGHGVRQVRGRGLLIGLQLDADIDAHDFAFAL AERGVLTKDTNGNVVRLTPPLVIGEAELALALEAIRQTLAGWPRRKVA