Protein Info for ABZR87_RS05145 in Ralstonia sp. UNC404CL21Col

Annotation: copper chaperone PCu(A)C

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 165 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF04314: PCuAC" amino acids 32 to 135 (104 residues), 125.9 bits, see alignment E=3.3e-41

Best Hits

KEGG orthology group: K09796, hypothetical protein (inferred from 96% identity to rpi:Rpic_3713)

Predicted SEED Role

"Copper metallochaperone, bacterial analog of Cox17 protein" in subsystem Biogenesis of cytochrome c oxidases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (165 amino acids)

>ABZR87_RS05145 copper chaperone PCu(A)C (Ralstonia sp. UNC404CL21Col)
MMTSRSIRSSACLAVLTAGLLASAAAFAQVTVQDAWVRGTVPGQTSSGAFMTLQSADGAK
VVGVSTPVAGTAEIHEMKMEGNVMRMRAVQALELPKGQTVQLKPGGYHVMLMDLKQPLAK
DATVPLTLKVELADKRVVEQKVEARVRDLTAGNMPAMNHGGEHKH