Protein Info for ABZR87_RS05015 in Ralstonia sp. UNC404CL21Col

Annotation: penicillin-binding protein 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 transmembrane" amino acids 18 to 38 (21 residues), see Phobius details TIGR03423: penicillin-binding protein 2" amino acids 17 to 627 (611 residues), 789.9 bits, see alignment E=7.7e-242 PF03717: PBP_dimer" amino acids 61 to 251 (191 residues), 156 bits, see alignment E=1.5e-49 PF00905: Transpeptidase" amino acids 283 to 623 (341 residues), 208.4 bits, see alignment E=1.4e-65

Best Hits

KEGG orthology group: K05515, penicillin-binding protein 2 (inferred from 97% identity to rpi:Rpic_3687)

Predicted SEED Role

"Penicillin-binding protein 2 (PBP-2)" in subsystem Peptidoglycan Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (800 amino acids)

>ABZR87_RS05015 penicillin-binding protein 2 (Ralstonia sp. UNC404CL21Col)
MTEIRNVEQELSRFRLRLAAAALFVLVCFGLLLARFFWLQQVKHEQYSAKAEDNRISVAP
IEPNRGIIMDRNGVVLARNYSAYTLEITPSKLQDTLDNTIDQLAQVVDIQPRDRRRFKRL
MEDARSFESLPIRSQLTDQEVARFSAQRFRFPGVDVHARLFRQYPLGDSASHVIGYIGRI
SERDLDRIDNMSDANSQPGVAYDPRKDSNNYSGTEYIGKVGIEQSYETELHGLTGYEEVE
VSAGGRPIRTLSTSQATPGNNLILSLDINLQRLAEQLFGNRRGALVAIEPETGDILAFVS
KPTFDPNLFIEGIDSATWNELNNSPDKPLLNRPLRGTYPPGSTYKPFMALGALELGKRTP
QWGMADPGSFTLGNHTFRDDVPGGHGWVDMYRSIVASCDTYYYRLANDMGVNAIHDFMKP
FGFGQVTGIDIEGERTGILPSTEWKRKAYKRPEQQKWYDGETISLGIGQGYNNFTILQLA
HAISTLANNGVVMKPHLVKAVEDSLSKSRSLTVPTESYRIPLKQANIDVIKRAMVGVNQA
GTAAKAFIGAQYVSAGKTGTAQVYSLGKNEKYNHHAIPENKRDHALFEAFAPADHPKIAL
ALIVENAGFGAASAAPIARAVMDYYLTGKWPAELAATAPKPQQQPPVDTPSVFSTGKTAT
IASATAAPPVAAEPASGVAAASGVAASAAGATAASALAASSITAGAARSVPPLSPDLVAP
ALREAGTSAEAVAPATLDAQVLQALSHAQPAPELPPRGRGNAAAPASAPATAPKGAKDAK
PGNKPAPKPAQKPASKPAAP