Protein Info for ABZR87_RS04985 in Ralstonia sp. UNC404CL21Col

Annotation: DNA-processing protein DprA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 401 TIGR00732: DNA protecting protein DprA" amino acids 96 to 312 (217 residues), 252.9 bits, see alignment E=9.7e-80 PF02481: DNA_processg_A" amino acids 102 to 303 (202 residues), 251.4 bits, see alignment E=5.2e-79 PF17782: DprA_WH" amino acids 336 to 395 (60 residues), 67.5 bits, see alignment E=8.6e-23

Best Hits

KEGG orthology group: K04096, DNA processing protein (inferred from 97% identity to rpf:Rpic12D_3358)

Predicted SEED Role

"Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (401 amino acids)

>ABZR87_RS04985 DNA-processing protein DprA (Ralstonia sp. UNC404CL21Col)
MTDASQVAAPAAADSTASLSCTRDPAELAAWLRLTETPGVGPVAARQLLAAFGLPQDIFA
QPYAALAKVLPERQARAVLAEPDDTLSALIERTVAWVNEPGNAIFTLADRGYPPRLLELP
DPPTLLYTKGDASLLRAAAVGVVGARSATAAGIENARAFSQALSAASVTIVSGLALGIDA
AAHEGALAGPGSTIAVVGTGLDIVYPARNRALAHRIAEAGVIISEYPLGMGARAENFPRR
NRLISGLARGLLVVEAAAQSGSLITARLAAEQGRDVFAIPGSIHSPLAKGCHLLIKQGAK
LVETAADILDELGWGRAATPAKRATRTATVQAPEAAPAPARAAPSAAETTLLDALGFDPV
DLDTLCERTGQAAAPLSAQLLALELDGRVERQPGGRFLRLP