Protein Info for ABZR87_RS04845 in Ralstonia sp. UNC404CL21Col

Annotation: alkaline phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 485 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF00245: Alk_phosphatase" amino acids 45 to 483 (439 residues), 342.1 bits, see alignment E=5e-106 PF00884: Sulfatase" amino acids 47 to 381 (335 residues), 29.1 bits, see alignment E=6.4e-11

Best Hits

KEGG orthology group: K01077, alkaline phosphatase [EC: 3.1.3.1] (inferred from 98% identity to rpf:Rpic12D_3331)

Predicted SEED Role

"Alkaline phosphatase (EC 3.1.3.1)" in subsystem Phosphate metabolism (EC 3.1.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.1

Use Curated BLAST to search for 3.1.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (485 amino acids)

>ABZR87_RS04845 alkaline phosphatase (Ralstonia sp. UNC404CL21Col)
MHNHKLTKYAAAAAAALAMAACGSDGTSATGSATPDTTPPSTMPAKNVVFFLGDGMGLTT
MTAARIYKVGEDGELTMDTLPETGFVRTFSNNAQVTDSAPSMSAYMTGVKMNNEVISMSP
DTMAYDAGGKDYISGADSTCPSGNGKPVTTLLELMKAAGYGTGVVTTTRITHATPAATYS
HICHRDGENTIAAQLTPAGKGFNAALGDGVDVVFGGGRKHFQPTTAGGARTDGRDLIAEL
KAGGYRYASNKAEFDTLQATDGKVVGLFTSSHMSYDLDRDPSKEPSLGEMTNKAIDVLAA
KKKGFFLMVEGGRIDHALHETTARKALQDTVAFDSAIRGAIDKLNTIDPGLKNTLIVVTA
DHDHTLVLNGYAKRTGPTSDSNPGVLGLLKNYVTGANATDTGGNPFTIIGFGTGENRPAT
RGALTDVAVYDKSYHQEAVIPVAPGGETHGGTDVFIGARGLGAERFTGTMDNTEVFGLIK
QAVGL