Protein Info for ABZR87_RS04760 in Ralstonia sp. UNC404CL21Col

Annotation: GMC family oxidoreductase N-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 576 PF00732: GMC_oxred_N" amino acids 12 to 315 (304 residues), 168.1 bits, see alignment E=6.6e-53 PF05834: Lycopene_cycl" amino acids 13 to 47 (35 residues), 24.2 bits, see alignment (E = 4.4e-09) PF00890: FAD_binding_2" amino acids 212 to 281 (70 residues), 24.7 bits, see alignment E=3.2e-09 PF05199: GMC_oxred_C" amino acids 407 to 545 (139 residues), 139.4 bits, see alignment E=3e-44

Best Hits

KEGG orthology group: None (inferred from 98% identity to rpf:Rpic12D_3313)

Predicted SEED Role

"Choline dehydrogenase (EC 1.1.99.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (EC 1.1.99.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.99.1

Use Curated BLAST to search for 1.1.99.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (576 amino acids)

>ABZR87_RS04760 GMC family oxidoreductase N-terminal domain-containing protein (Ralstonia sp. UNC404CL21Col)
MATDLPTSALTFDYVIVGAGSAGCALASRLTEDPDVTVALLEAGPHDHHLSVWVPAGCAA
SLPFKNKRNYGFQTVPQAGLGGRQGYQPRGRGLGGSSSLNAMIYIRGTPSDYNHWAALGC
TGWSWNDVLPYFKRSEGNERFAGRDDDALHGGTGPLHVSDLRTGNPIAQRFVEAGVAAGY
RRNNDFNGPEQEGVGPYQVTQYNGERWNAARAYLHGGNKADATFSRNRRQLTVMPDTQAL
RIVFEGKRAAGVVVERAGRTETLRARREVIVSSGAFGSPQLLMASGVGPAEHLRSLGIPV
VHDLPGVGQNLQDHLDIILHKKVFNLDLIGYSARGSAHMLGQILRYRRERRGMLATNFAE
AGGFIKSRPDLADPDLQLHFVVAMADNHNRTFNYGHGYSCHVCVLRPKSRGEVRLASADT
RDAPLIDPKFLSDPEDMAGMLAGFRAVKSIFAQRPLADLGGRELYSGNIRGDGSDDEAVR
ALIRQHADTIYHPVGTCKMGSADDAMAVVDPELRVRGLTGLRVIDGSVMPTLIGGNTNAP
IIMIAERAADLMRQGGRPTLNVVSSIAAQAAPAEVH