Protein Info for ABZR87_RS04560 in Ralstonia sp. UNC404CL21Col

Annotation: hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 199 PF00857: Isochorismatase" amino acids 16 to 191 (176 residues), 133.7 bits, see alignment E=4e-43

Best Hits

Swiss-Prot: 60% identical to YECD_ECO57: Uncharacterized isochorismatase family protein YecD (yecD) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 93% identity to rpf:Rpic12D_3277)

Predicted SEED Role

"Nicotinamidase/isochorismatase family protein" in subsystem NAD and NADP cofactor biosynthesis global

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (199 amino acids)

>ABZR87_RS04560 hydrolase (Ralstonia sp. UNC404CL21Col)
MSEPLQTLSALSAKTTALVLIDLQRGILPFAQGPHTAEQVLGASAKLAKRFRELGAPVVL
VRVGWASDYADAPRHPVDRPTPTQPGGLPPQWWEQPAELEVAATDIQITKRQWGAFYGTE
LDLQLRRRGVTTIVLGGISTHVGVESTARAAWEHGYALVLAEDAMSSNDAAMHRSSVENV
FPRLGRVRDTDTILAALTA