Protein Info for ABZR87_RS04405 in Ralstonia sp. UNC404CL21Col

Annotation: chromate resistance protein ChrB domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 320 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF20229: ChrB_N" amino acids 23 to 149 (127 residues), 30.7 bits, see alignment E=2.9e-11 PF09828: ChrB_C" amino acids 185 to 313 (129 residues), 152 bits, see alignment E=1.2e-48

Best Hits

Swiss-Prot: 65% identical to CHRB1_CUPMC: Protein ChrB (chrB1) from Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)

KEGG orthology group: None (inferred from 95% identity to rpf:Rpic12D_3250)

Predicted SEED Role

"Chromate resistance protein ChrB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (320 amino acids)

>ABZR87_RS04405 chromate resistance protein ChrB domain-containing protein (Ralstonia sp. UNC404CL21Col)
MTASPDSWLLLIVSLPTARATARMRIWRAIKAIGCAALRDGVYLLPARAEHAAQLNDLAD
ETLQEDGQAWVLRVQAGDAAEDAAYRALFDRSPDYAEWLAELSEARKTLPDLPAAERNRL
LRRHARAYEAIRKIDFFSNEATVRADAQWRDFAAAVEATHSPGEPRAAAGSIPRRDRTQY
QGRLWATRRHLWVDRVASAWLIHRFIDPHARFLWLDSPADCPADALGFDFDGAAFTHVGE
RVSFEVLVASFGLDDDAGLARLGAMVHALDVGGAATPEAGGFEAILAGARKRVADDDALL
AEIGSVLDSLYVHFSGSRKP