Protein Info for ABZR87_RS04240 in Ralstonia sp. UNC404CL21Col

Annotation: heavy-metal-associated domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 70 PF00403: HMA" amino acids 7 to 64 (58 residues), 56.8 bits, see alignment E=1.2e-19

Best Hits

Swiss-Prot: 42% identical to COPZ_STAAB: Copper chaperone CopZ (copZ) from Staphylococcus aureus (strain bovine RF122 / ET3-1)

KEGG orthology group: K07213, copper chaperone (inferred from 94% identity to rpi:Rpic_3544)

Predicted SEED Role

"Copper chaperone" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (70 amino acids)

>ABZR87_RS04240 heavy-metal-associated domain-containing protein (Ralstonia sp. UNC404CL21Col)
MTTSSTTFSVTGMSCGHCVSAVTRAVQQVDAGANVQVDLDKQTVAVTSGASADAVKAAIE
QAGYPVKAFA