Protein Info for ABZR87_RS04205 in Ralstonia sp. UNC404CL21Col

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 402 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF13458: Peripla_BP_6" amino acids 30 to 365 (336 residues), 381.5 bits, see alignment E=8.4e-118 PF13433: Peripla_BP_5" amino acids 31 to 352 (322 residues), 69.6 bits, see alignment E=4e-23 PF01094: ANF_receptor" amino acids 53 to 348 (296 residues), 33.7 bits, see alignment E=3.2e-12

Best Hits

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 99% identity to rpi:Rpic_3537)

Predicted SEED Role

"Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (402 amino acids)

>ABZR87_RS04205 ABC transporter substrate-binding protein (Ralstonia sp. UNC404CL21Col)
MTLKKLAGALMAVGLGAAAFGAHAQVSGDKVKIGYITDLSGLYADIDGQGGVEAVKMAIE
DAGGKVLGKPIELVTADHQNKADIAASKAREWMDQQGLDMLLGGTNSATGLAMNKVASEK
KRVFIDIGAGTARLTNEECTPYTIHYAYDTVALAKGTGSAVVKQGGKSWFFLTADYAFGH
SLENDTTAVVKANGGTVVGSVKHPLSASDFSSYLLQAQSSKAQILGLANAGGDTINSIKA
AKEFGITKSMKIAGLLMFINDVHSLGLQTAEGLLMTDSWYWDMNDATRKFANRYFMKMKK
MPSSLQAADYSAVSNYIKAVAAAGTDDPDKVIAQLKKTKIDDFYTKGTIRQDGRAIHDMY
LLQVKSPAESKKPWDYLKVVATIPGEQAFTTPAESKCSLMKK