Protein Info for ABZR87_RS03815 in Ralstonia sp. UNC404CL21Col

Annotation: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase" amino acids 20 to 293 (274 residues), 219.1 bits, see alignment E=3.8e-69 PF00590: TP_methylase" amino acids 20 to 221 (202 residues), 107.6 bits, see alignment E=4.5e-35

Best Hits

Swiss-Prot: 46% identical to RSMI_NEIMA: Ribosomal RNA small subunit methyltransferase I (rsmI) from Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)

KEGG orthology group: K07056, (no description) (inferred from 97% identity to rpf:Rpic12D_3136)

Predicted SEED Role

"rRNA small subunit methyltransferase I" in subsystem Heat shock dnaK gene cluster extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (300 amino acids)

>ABZR87_RS03815 16S rRNA (cytidine(1402)-2'-O)-methyltransferase (Ralstonia sp. UNC404CL21Col)
MSDPDWTLLAHDQHYPAGALYVVATPIGNAADVSLRARYVLGIVDAVACEDTRNTGQLLN
RLGLSRPMLAAHEHNEREAAARIVARLAQGERIAYVSDAGTPGVSDPGSRIVEAVRAAGQ
RVIPLPGASAVVTALSAAGELLDTSGGQFTFVGFLPPKAGQRDAAIRQWVAHGPAWVLYE
APHRIEATLAALAEHLPARRILIGRELTKLFEEIVVLPAADAPAWLAADASHGKGEFVLV
VEGAGAQDAAPNAMAADQVLRLLLAELPAKRAAKLAGAITGASVDALYQSALASKNEGKD