Protein Info for ABZR87_RS03290 in Ralstonia sp. UNC404CL21Col

Annotation: xanthine dehydrogenase family protein molybdopterin-binding subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01315: Ald_Xan_dh_C
  • amino acids 18 to 126 (109 residues), 79.3 bits, E=4e-26
• PF02738: MoCoBD_1
  • amino acids 154 to 379 (226 residues), 209.2 bits, E=8.1e-66
• PF20256: MoCoBD_2
  • amino acids 403 to 675 (273 residues), 188 bits, E=4.2e-59

Best Hits

KEGG orthology group: K11177, xanthine dehydrogenase YagR molybdenum-binding subunit [EC: 1.17.1.4] (inferred from 95% identity to rpf:Rpic12D_3027)

Predicted SEED Role

"Periplasmic aromatic aldehyde oxidoreductase, molybdenum binding subunit YagR"

MetaCyc Pathways

• purine nucleotides degradation II (aerobic) (11/11 steps found)
• adenosine nucleotides degradation II (5/5 steps found)
• guanosine nucleotides degradation III (4/4 steps found)
• inosine 5'-phosphate degradation (4/4 steps found)
• ureide biosynthesis (6/7 steps found)
• guanosine nucleotides degradation II (3/4 steps found)
• adenosine nucleotides degradation I (5/8 steps found)
• guanosine nucleotides degradation I (2/4 steps found)
• purine nucleobases degradation II (anaerobic) (16/24 steps found)
• superpathway of guanosine nucleotides degradation (plants) (3/6 steps found)
• purine nucleotides degradation I (plants) (7/12 steps found)
• superpathway of purines degradation in plants (11/18 steps found)
• caffeine degradation III (bacteria, via demethylation) (1/7 steps found)
• theophylline degradation (1/9 steps found)
• caffeine degradation IV (bacteria, via demethylation and oxidation) (1/10 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.17.1.4

Use Curated BLAST to search for 1.17.1.4

Protein Sequence (732 amino acids)

>ABZR87_RS03290 xanthine dehydrogenase family protein molybdopterin-binding subunit (Ralstonia sp. UNC404CL21Col)
MSNVGQPLDRTDGLLKVTGQARYSAEFQVPRLVHAVLVQSTVPAGRITRVDTHVAQAMPG
VLLVMTHENAPRLPNGGKPALEPPAGRALSLLQDDQVHYNGQPVALVVGDTLEHAQAAAR
MVRVEVAQQAARLDFETARADAHSPGKVQGQSADTTRGDVVAGMAQAAQRIEAVYGTPME
THNPMEPHATIAVWEGDSLTLYDSTQYVSGVRRTVAKTLGLSPDKLRVVCPFVGGGFGCK
GSVWSHVVLAAMAARQVGRPVKLVLERPQMFGPVGGRPRTEQRIALGAASDGRFTAISHD
SLTTTSMIEDWTEPCAIVTRMLYDTPNQRTTHRLARLNVGTPTFQRAPGEATGTFALEVA
LDEMAYALGIDPVELRLRNDAAQDPEKRIPWSSKSLAACYRAGAERFGWARRNPQPGSMR
EGNTRVGWGMATATYPANRSAAAATARYLPDGTAQVESGSQDLGTGTYTVMTQVAADAMG
MPVDRVHFGLGDTRMPEAPVSGGSQSVASVSPAVQAAGQQARDALIAAAIADASSPLHGL
AAGDITVADGVLTARGGAREPVAAVVARHGSPIEVTAKVQPGEEKQKFSMHSFGAVFVEV
HVDADLGVVRVPRIVGSYGVGRLLNAKTGRSQLMGGIVWGMGMALFEESLLDTRYGRTVN
NNLAEYHVPVNADVPDIDILVLDEADAYVNPLGAKGIGEIGITGVPAAIANAVYHATGRR
VRELPITLDKLI