Protein Info for ABZR87_RS03195 in Ralstonia sp. UNC404CL21Col

Annotation: cation diffusion facilitator family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 382 transmembrane" amino acids 90 to 111 (22 residues), see Phobius details amino acids 123 to 146 (24 residues), see Phobius details amino acids 167 to 184 (18 residues), see Phobius details amino acids 190 to 209 (20 residues), see Phobius details TIGR01297: cation diffusion facilitator family transporter" amino acids 19 to 301 (283 residues), 227.5 bits, see alignment E=1e-71 PF01545: Cation_efflux" amino acids 23 to 216 (194 residues), 161.8 bits, see alignment E=1.8e-51 PF16916: ZT_dimer" amino acids 220 to 299 (80 residues), 66.9 bits, see alignment E=1.4e-22

Best Hits

KEGG orthology group: None (inferred from 96% identity to rpf:Rpic12D_3009)

Predicted SEED Role

"Cobalt-zinc-cadmium resistance protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (382 amino acids)

>ABZR87_RS03195 cation diffusion facilitator family transporter (Ralstonia sp. UNC404CL21Col)
MTPTSPTTLSAAARQQSAERSTLVSAGVNCLLSAGQIAAGLWSHSQGLVADGLHTLSDLI
ADGIVFIANRNSHKGPDEDHQYGHARYENAASLGLGLLLVGAGAGMIWAAVESLRSPQGP
APVHGLALVVALIALAAKEGLFRYMLAVAKRINSRMLIANAWHARSDAVSSLVAAVGVAG
NLMGYHWLDPLAACVVGLMIGRVGVRFGWEALNDLMDRALPPAQVEAIRASLEATPGVIN
VHDLRTRVTGDQALVDAHIEVDPRVSVSEGHAIAVRARTNALTAHTAMAVLDVQIHVDPR
EHIATDPVPLPDRDALHAVLAQLLPPGTPLDARHCVLHYVDGAVEVDLVLPPALAGELRR
IADAVHARWDGLVRLRVLVTDA