Protein Info for ABZR87_RS03160 in Ralstonia sp. UNC404CL21Col

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 417 transmembrane" amino acids 28 to 52 (25 residues), see Phobius details amino acids 67 to 87 (21 residues), see Phobius details amino acids 96 to 117 (22 residues), see Phobius details amino acids 123 to 143 (21 residues), see Phobius details amino acids 154 to 173 (20 residues), see Phobius details amino acids 183 to 204 (22 residues), see Phobius details amino acids 236 to 255 (20 residues), see Phobius details amino acids 267 to 288 (22 residues), see Phobius details amino acids 300 to 318 (19 residues), see Phobius details amino acids 324 to 345 (22 residues), see Phobius details amino acids 357 to 376 (20 residues), see Phobius details amino acids 384 to 406 (23 residues), see Phobius details PF07690: MFS_1" amino acids 34 to 279 (246 residues), 108.8 bits, see alignment E=3e-35 amino acids 264 to 413 (150 residues), 39.7 bits, see alignment E=2.9e-14 PF00083: Sugar_tr" amino acids 64 to 214 (151 residues), 34 bits, see alignment E=1.7e-12

Best Hits

Swiss-Prot: 45% identical to YYBF_BACSU: Uncharacterized MFS-type transporter YybF (yybF) from Bacillus subtilis (strain 168)

KEGG orthology group: K08224, MFS transporter, YNFM family, putative membrane transport protein (inferred from 97% identity to rpf:Rpic12D_3002)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (417 amino acids)

>ABZR87_RS03160 MFS transporter (Ralstonia sp. UNC404CL21Col)
MNAPLSSSPAIEPADPSRWLVRGHPGYLRANLALFAAGFSTFSLLYCVQPLMPLLAHDFG
LTPAQTSLVLSVSTLLLAFAILFAGLLSESIHRKTLMGVSLVLSSALTLAAAVLPGWHGL
LATRALLGVVLGGVPAVAMAYLAEEVHPQGLGMAMGLYVGGTAFGGMAGRVLTGAVADHF
GWRAAIGFTGMLGLLAALAFLWLLPPSRRFVPRKGVALGDLFDTLGAHLREPGLRALFAM
GFLLMGGFVTIYNYASFHLLDAPYALSQTAVGGIFMVYLLGIGASAWFGRLADRHGRGRM
LLAGTALMSTGVLMTLAGPLVLVIGGIALLTFGFFGAHAVASGWVGRRAQRAKGQAAALY
LLAYYLGSSLIGTTGGKLYAPWGWPGVVTLVMGCMACALGTAAWLWRRAPMPPGAKR