Protein Info for ABZR87_RS02545 in Ralstonia sp. UNC404CL21Col

Annotation: outer membrane lipid asymmetry maintenance protein MlaD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 173 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details TIGR04430: outer membrane lipid asymmetry maintenance protein MlaD" amino acids 3 to 147 (145 residues), 202.2 bits, see alignment E=1.6e-64 PF02470: MlaD" amino acids 38 to 116 (79 residues), 76.7 bits, see alignment E=6.8e-26

Best Hits

Swiss-Prot: 53% identical to MLAD_HAEIN: Intermembrane phospholipid transport system binding protein MlaD (mlaD) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02067, putative ABC transport system substrate-binding protein (inferred from 95% identity to rpf:Rpic12D_2891)

Predicted SEED Role

"Uncharacterized ABC transporter, periplasmic component YrbD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (173 amino acids)

>ABZR87_RS02545 outer membrane lipid asymmetry maintenance protein MlaD (Ralstonia sp. UNC404CL21Col)
MRKSVLDFWVGLFVLVGIIALLFLALKAGNMSSFSFAKTYQVKAAFDNIGGLKVRAPVKS
SGVVVGRVSQILFDDKSYQAIAVLEMDQRYQFPKDSSAKILTSGLLGEQYVGIEPGGDSA
MLASGSKITMTQSAVVLENLISQFLYSKAADAGAGSGNGGAGAAKPAEGSGSK