Protein Info for ABZR87_RS02330 in Ralstonia sp. UNC404CL21Col

Annotation: cytochrome o ubiquinol oxidase subunit I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 659 transmembrane" amino acids 16 to 38 (23 residues), see Phobius details amino acids 58 to 78 (21 residues), see Phobius details amino acids 103 to 127 (25 residues), see Phobius details amino acids 139 to 161 (23 residues), see Phobius details amino acids 189 to 213 (25 residues), see Phobius details amino acids 227 to 253 (27 residues), see Phobius details amino acids 274 to 298 (25 residues), see Phobius details amino acids 310 to 333 (24 residues), see Phobius details amino acids 346 to 368 (23 residues), see Phobius details amino acids 380 to 403 (24 residues), see Phobius details amino acids 415 to 439 (25 residues), see Phobius details amino acids 456 to 478 (23 residues), see Phobius details amino acids 493 to 516 (24 residues), see Phobius details amino acids 592 to 619 (28 residues), see Phobius details TIGR02843: cytochrome o ubiquinol oxidase, subunit I" amino acids 2 to 648 (647 residues), 1183.1 bits, see alignment E=0 PF00115: COX1" amino acids 56 to 504 (449 residues), 501.9 bits, see alignment E=8e-155

Best Hits

Swiss-Prot: 73% identical to CYOB_PSEAE: Cytochrome bo(3) ubiquinol oxidase subunit 1 (cyoB) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K02298, cytochrome o ubiquinol oxidase subunit I [EC: 1.10.3.-] (inferred from 100% identity to rpf:Rpic12D_2813)

MetaCyc: 71% identical to cytochrome bo3 subunit 1 (Escherichia coli K-12 substr. MG1655)
RXN-21817 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (659 amino acids)

>ABZR87_RS02330 cytochrome o ubiquinol oxidase subunit I (Ralstonia sp. UNC404CL21Col)
MFGKLSLEAIPLHEPIVVVTVSAILLGGAGLFGLITYLKKWTYLWNEWITSVDHKKIGVM
YCILAIVMLLRGFADAIMMRSQLAVASGGGAGYLPPEHYDQIFTAHGVIMIFFMAMPLMT
GLINLIVPLQIGARDVAFPFLNTLSFWLAAAGVVLINVSLGVGEFARTGWLAYPPLSELA
YSPGVGVDYYIWALQISGLGTLLTGVNFVATIFKMRAPGMTLMRMPIFTWTALCANILIV
AAFPVLTVALALLGADRYLDMHFFTNDGGGNAMLYVNLIWIWGHPEVYILILPAFGMFSE
IVSTFSRKKLFGYTSMVWATAGITVLSFLVWLHHFFTMGSGANVNAFFGIATMIISIPTG
VKIFNWLFTMYRGRVELNSMMLWTIGFMITFVIGGMTGVLLAVPGADFLLHNSLFLIAHF
HNTIIGGVVFGYLAGITYWFPKAFGFKLDEKWGKRAFWCWFVGFYTAFMPLYVLGFMGMT
RRLNHTDNPAWQPWLIVAVIGAAIIACGIASQLIQIFVSIRNRHALADLTGDPWGGRTLE
WATSSPPAHYNFARVPVIRDIDAFADMKARGEVLTQVAPSYEKIHMPKNTGAGFFIGMFS
IVMGFALIWHIWWMAVLGLVGMIGSFILRSNNDDIDYYVPAHEVHETESAYFQRIGSQA