Protein Info for ABZR87_RS02310 in Ralstonia sp. UNC404CL21Col

Annotation: energy-dependent translational throttle protein EttA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 555 TIGR03719: ATP-binding cassette protein, ChvD family" amino acids 2 to 552 (551 residues), 983.9 bits, see alignment E=2.1e-300 PF00005: ABC_tran" amino acids 22 to 191 (170 residues), 91.2 bits, see alignment E=1.9e-29 amino acids 340 to 473 (134 residues), 90.7 bits, see alignment E=2.7e-29 PF12848: ABC_tran_Xtn" amino acids 230 to 306 (77 residues), 45.3 bits, see alignment E=1.5e-15

Best Hits

Swiss-Prot: 73% identical to ETTA_HAEIN: Energy-dependent translational throttle protein EttA (ettA) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K06020, sulfate-transporting ATPase [EC: 3.6.3.25] (inferred from 100% identity to rpi:Rpic_3159)

Predicted SEED Role

"ABC transporter ATP-binding protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.25

Use Curated BLAST to search for 3.6.3.25

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (555 amino acids)

>ABZR87_RS02310 energy-dependent translational throttle protein EttA (Ralstonia sp. UNC404CL21Col)
MSQYVFTMNRVGKIVPPKRQILKDISLSFFPGAKIGVLGLNGSGKSTVLKIMAGLDKDIE
GEATPMPNLNIGYLPQEPQLDPAKTVREEVESGLGEVMDAQKQLEAIYAAYAEEGADFDK
LAEEQARLEAIIAAGSGDNVELQLEIAADALRLPPWDAKIEHLSGGEKRRVALCKLLLSR
PDMLLLDEPTNHLDAESVDWLEQFLTRFPGTVVAVTHDRYFLDNAAEWILELDRGHGIPW
KGNYSSWLDQKETRLKQEESSESARQKALKKELEWVRQNPKGRQAKSKARLARFDELNSQ
EYQKRNETQEIFIPAGERLGNEVIEFQNVSKSYGDRLLIDNLSFTIPPGAIVGIIGPNGA
GKSTLFRMITGKEQPDSGTIKIGPTVKLAYVDQSRDALSADKTVFEEISNGSDILTVGRY
ETPSRAYIGRFNFKGGDQQKHVGTLSGGERGRLHLAKTLISGGNVLLLDEPSNDLDVETL
RALEDALLEFAGCVMVISHDRWFLDRIATHIIAFEGDSHVEFFPGNYQEYEADKKKRLGE
EGAKPKRIRYKPVTR