Protein Info for ABZR87_RS02265 in Ralstonia sp. UNC404CL21Col

Annotation: Grx4 family monothiol glutaredoxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 103 TIGR00365: monothiol glutaredoxin, Grx4 family" amino acids 5 to 102 (98 residues), 153.1 bits, see alignment E=9.1e-50 PF00462: Glutaredoxin" amino acids 17 to 82 (66 residues), 74.6 bits, see alignment E=2.9e-25

Best Hits

Swiss-Prot: 58% identical to YC64L_SYNY3: Uncharacterized monothiol glutaredoxin ycf64-like (slr1846) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K07390, monothiol glutaredoxin (inferred from 98% identity to rpi:Rpic_3150)

Predicted SEED Role

"Glutaredoxin-related protein" in subsystem Glutaredoxins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (103 amino acids)

>ABZR87_RS02265 Grx4 family monothiol glutaredoxin (Ralstonia sp. UNC404CL21Col)
MSTTHEKIDQIVKGHPVVLFMKGTAQFPMCGFSGRAIQILKACGVDRPHTVNVLEDDEIR
QGIKDYANWPTIPQLYIKGEFIGGSDIMMEMYQSGELQPLLAA