Protein Info for ABZR87_RS01755 in Ralstonia sp. UNC404CL21Col

Annotation: ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 679 transmembrane" amino acids 46 to 66 (21 residues), see Phobius details amino acids 85 to 103 (19 residues), see Phobius details amino acids 115 to 141 (27 residues), see Phobius details amino acids 144 to 169 (26 residues), see Phobius details amino acids 180 to 205 (26 residues), see Phobius details PF00512: HisKA" amino acids 421 to 494 (74 residues), 47.9 bits, see alignment E=1.1e-16 PF02518: HATPase_c" amino acids 547 to 636 (90 residues), 58.8 bits, see alignment E=7e-20

Best Hits

KEGG orthology group: K02668, two-component system, NtrC family, sensor histidine kinase PilS [EC: 2.7.13.3] (inferred from 97% identity to rpf:Rpic12D_2643)

Predicted SEED Role

"Two-component sensor PilS" in subsystem Type IV pilus

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (679 amino acids)

>ABZR87_RS01755 ATP-binding protein (Ralstonia sp. UNC404CL21Col)
MTPEASGAARATPSGARSLLSRLNAWRALRSVWLEPDPPEFQWRLLRYFAFSRAAVALVL
LLFVMVPREHNEAVGLPNGDTLLSLTLPYLAMALLILAAAGWWRTRFQFRVRLDVVLDLL
FLGLAYATLSRLSASVAMVLLMPVLAAGALTSLLFALFTAAVASIVVLADPFLQMLNDGV
IAPGLASAGLYGLVYMMAASMMYGLSHRQIAQERLTMARERELRLQQLVNRLMVYDMQDG
VMLVRADGRVVAANPAAAMLLGVPQSAFVGSGAMLFDLKDVPHLRPLLETLRQWLRRKSR
PADGTGDDDAPRILDLLPIAAGGRAGRAMLSARLRLRFILPSLANLRSVYMDSLVSSIGL
GLPGEGGEMRARIPSADAITQGWSVDDEAFLRHELHDTVLVHVESWERVAEQAQQEKLAS
MGRLVASVAHQIRNPLAAISQAAELLDDPGDGQEGGAHMRPESGGVETRLLRIIRDNVRR
LDQVVADVLMLSRRPRGERVRVQLAQVLPEVVDRWRAEALRRAGEATEINPNLVRVAVDL
DKPVLFDPAQLQQVVGNMLDNALRYCRRVPGSIQLAAYALDDTHAELVIWNDGPEVPTEQ
QRSLFEPFFTNDAQGTGLGLYMARELCSANDAQIRYGAIALESLLDRTGALTMEARDTLP
RRAFVITLMFDQPALAVTE