Protein Info for ABZR87_RS01710 in Ralstonia sp. UNC404CL21Col

Annotation: DMT family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details transmembrane" amino acids 44 to 66 (23 residues), see Phobius details amino acids 78 to 98 (21 residues), see Phobius details amino acids 104 to 122 (19 residues), see Phobius details amino acids 129 to 145 (17 residues), see Phobius details amino acids 156 to 173 (18 residues), see Phobius details amino acids 185 to 203 (19 residues), see Phobius details amino acids 209 to 232 (24 residues), see Phobius details amino acids 244 to 264 (21 residues), see Phobius details amino acids 270 to 290 (21 residues), see Phobius details PF00892: EamA" amino acids 155 to 284 (130 residues), 65.2 bits, see alignment E=3.9e-22

Best Hits

Swiss-Prot: 48% identical to RHTA_SALTS: Threonine/homoserine exporter RhtA (rhtA) from Salmonella typhimurium (strain SL1344)

KEGG orthology group: None (inferred from 99% identity to rpf:Rpic12D_2634)

MetaCyc: 49% identical to L-threonine/L-homoserine exporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-242; TRANS-RXN0-0244

Predicted SEED Role

"Integral membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (298 amino acids)

>ABZR87_RS01710 DMT family transporter (Ralstonia sp. UNC404CL21Col)
MSSAASASATSTTTTSPWMPILALMGSMASVCLGNSFAKTLFPVLGAAGTVTYRVTIGAV
ILLAFWRPWRLHLSRADAGRIALYGVTLASMNLLFYLSLQRLPIGIAIAIEFTGPLVLAV
LLSRRALDFVWIGLAVAGLLMLTVADKSVGQVDHLGAIYALAAGVCWALYILTGKNLGGL
HAGQATSIGMVVGALFAIPFGVAQAGSALLAPSLILAGLGIGLLSSAIPYSLEMVALKHL
PGKTFSVLLSLEPAIGALAGAIVLQEQLTGRQWVAILAIIAASAGCALTVRAPKPVQS