Protein Info for ABZR87_RS01615 in Ralstonia sp. UNC404CL21Col

Annotation: RNB domain-containing ribonuclease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 698 PF00773: RNB" amino acids 240 to 476 (237 residues), 113.5 bits, see alignment E=6.7e-37 amino acids 480 to 523 (44 residues), 40.1 bits, see alignment 1.4e-14

Best Hits

KEGG orthology group: K01147, exoribonuclease II [EC: 3.1.13.1] (inferred from 98% identity to rpi:Rpic_3023)

Predicted SEED Role

"Exoribonuclease II (EC 3.1.13.1)" in subsystem RNA processing and degradation, bacterial (EC 3.1.13.1)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 3.1.13.1

Use Curated BLAST to search for 3.1.13.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (698 amino acids)

>ABZR87_RS01615 RNB domain-containing ribonuclease (Ralstonia sp. UNC404CL21Col)
MQLLFEEGGEIRAGTVLSQQGEAYQVELPSAKRTKVKSRDVLLQFAQPSAGELSQAAQAL
SAEIDLDFLWECASAEEFGFTDLAGEYFGAGANATQQAALAIALHGSPIYFRRKGRGRYQ
RAPEDQLKAALAGLERKKQQAALQAEYEAELKAMRLPEAFRGKTLQLLFKPDKNSLEYKA
LDAACTALGLSPMRLMVAVGGIANARALHEARFLSECFPKGTGFPDVTVPEPVMELPAAD
VRAFSIDDVTTTEIDDAISVTPIDDATVRIGIHIAAPGFGIQRGEPLDVIARQRLSTVYF
PGDKITMLPESVVDRYTLQEGRACPALSLYVTVDRATWAVTASETRCESVTVAANLRHNL
LDDVITADALADGSGDYPFKAELAVLWPFVCALYDGRQQARIASGLKPEGAQKGDYSFYI
DPIPEEEGGGERVRIEQRKRGSPLDKIVAELMILANSTWGRMLADAGVPGIYRTQKAWGM
HRTRMQTYPAPHEGLGVAQYAWSTSPLRRYVDLVNQWQIAAVAQHGVTAKLIAPFKPKDA
DLLAAVADFEATYAAYADHQSTMERYWCLRWLKQENRTRMQAVVLKEGAVRFADIPLVTK
VPELAQTARGTHVVLDILETDEISLEVSCRVVEILAPAADAQAEAEAIEEELAEAETEAD
VPAEPQPAADGEEARAEAGAAVAPPPQDGETGGTPTAA