Protein Info for ABZR87_RS01575 in Ralstonia sp. UNC404CL21Col

Annotation: phosphatidylglycerophosphatase A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF04608: PgpA
  • amino acids 45 to 188 (144 residues), 113.9 bits, E=3.1e-37

Best Hits

Swiss-Prot: 42% identical to PGPA_HAEIN: Phosphatidylglycerophosphatase A (pgpA) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K01095, phosphatidylglycerophosphatase A [EC: 3.1.3.27] (inferred from 95% identity to rpi:Rpic_3015)

Predicted SEED Role

"Phosphatidylglycerophosphatase A (EC 3.1.3.27)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 3.1.3.27)

MetaCyc Pathways

• phosphatidylglycerol biosynthesis I (6/6 steps found)
• phosphatidylglycerol biosynthesis II (6/6 steps found)
• superpathway of phospholipid biosynthesis III (E. coli) (10/12 steps found)
• cardiolipin biosynthesis II (3/3 steps found)
• cardiolipin biosynthesis I (2/3 steps found)
• cardiolipin biosynthesis III (2/3 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (9/13 steps found)
• type I lipoteichoic acid biosynthesis (S. aureus) (5/17 steps found)
• superpathway of phospholipid biosynthesis II (plants) (10/28 steps found)

KEGG Metabolic Maps

• Glycerophospholipid metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.27

Protein Sequence (192 amino acids)

>ABZR87_RS01575 phosphatidylglycerophosphatase A (Ralstonia sp. UNC404CL21Col)
MMSSTPFPPSNPPGQAETVVLEAGQTAQVRRPTARFMFAHPARILALGFGSGLSPILPGT
VGTLYAWLIYVVLAPWISGPIWLLIAAVGFVIGIWACARTARDLGVADHGAMVWDEMVAF
WIVLAFVTPTTLGGQFAAFLWFRFFDMVKPAPIRYYDRTLKGFGVRGGYGVMVDDILAAS
YTLLVFALWRSF